Breast-to-infant gut axis overview

Diagram of maternal breast feeding infant showing human milk components affecting infant gut microbiome and immunity

This diagram illustrates the connection between the maternal breast and the infant gut, emphasizing how human milk components contribute to infant gut health and immune development. The left side depicts a cross-section of the lactating breast, highlighting key components of human milk such as antibodies (sIgA), oligosaccharides (HMOs), cytokines, microbes, and growth factors. Arrows indicate the transfer of these components from breast milk to the infant gut, where they promote a diverse microbiome, gut barrier development, and immune system maturation. An inset magnifies the gut microbiome to show its role in supporting immune development and maintaining gut health through a strong barrier and balanced microbial populations.

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